MK-677 vs Tesamorelin
MK-677 and Tesamorelin are compared here on the things that actually differ between them: what class each belongs to, what each acts on, how each is supplied and what each costs per milligram. Where the registry has no figure for one of them the row is left out rather than filled in.
Side by side
| MK-677 | Tesamorelin | |
|---|---|---|
| Class | Orally active ghrelin receptor agonist | Stabilised GHRH analogue |
| Acts on | A non-peptide growth hormone secretagogue active by mouth, studied for sustained elevation of GH and IGF-1 without injection. | A synthetic GHRH analogue with a trans-3-hexenoyl modification improving stability. Studied specifically in visceral adipose tissue reduction. |
| Supplied as | Oral liquid or capsule. | Lyophilised powder or pre-filled pen. |
| Half-life | Approximately 24 hours, which is why it is characterised as once-daily in study design. | Longer than sermorelin, though still measured in minutes to a couple of hours. |
| Storage | Cool, dry, out of direct light. | 2-8 C. |
| Listings | 1 | 2 |
| Price from | £36 | £55 |
What actually differs
The clearest difference is class: MK-677 is an orally active ghrelin receptor agonist, Tesamorelin is a stabilised GHRH analogue. They are not supplied the same way. MK-677 comes as an oral liquid or capsule, Tesamorelin as a lyophilised powder or pre-filled pen. Half-life differs as well: Approximately 24 hours, which is why it is characterised as once-daily in study design for MK-677 against Longer than sermorelin, though still measured in minutes to a couple of hours for Tesamorelin.
Quanta Pharma MK-677 (Ibutamoren) 12.5mgin stock£36
Quanta Pharma Tesamorelin 10mgout of stock£55- SerenQ Tesamorelin 10mg Peptide Penout of stock£65
Availability checked 2026-09-09. The product page carries live stock.